-
NYU Dataset
Intra-axonal Space Segmentation from 3D Scanning Electron Microscopy (SEM) of the Mouse Brain Genu of Corpus Callosum
- Authors
- Hong-Hsi LeeDmitry S. NovikovEls Fieremans
- Description
This dataset includes 3D scanning electron microscopy (SEM) images of a female mouse corpus callosum and MATLAB code for random walker (RaW) segmentations of myelinated axons. The code additionally characterizes inner axonal diameters and fiber orientation dispersion within segments of the intra-axonal spaces and myelin sheaths. In the study, a female 8-week-old C57BL/6 mouse was perfused trans-cardiacally...
- Subject
-
AnatomyNeuroscience
- Access Rights
- Free to All
-
NYU Dataset
Volume Electron Microscopy Reveals Connexin43 in Plakophilin-2 Deficient Hearts
- Authors
- Chantal J. M. van OpbergenJoseph SallChris PetzoldKristen Dancel-Manning2 more author(s)...
- Description
Previous studies showed an abundance of functional Connexin43 (Cx43) hemichannels consequent to loss of plakophilin-2 (PKP2) expression in adult murine hearts. This study combined pre-embedding immunolabeling with serial block-face scanning electron microscopy (SBF-SEM) to visualize and examine the gap junction plaque morphology. They used a murine model of cardiomyocyte-specific Tamoxifen (TAM) activated...
- Subject
-
Cell Physiology
- Access Rights
- Application RequiredAuthor Approval Required
